Highly Sensitive SensoLyte® HDACs and HATs Assay Kits for Epigenetics Research
Summary
Press Releases AnaSpec, EGT Group Press Release Receive press releases from AnaSpec, EGT Group: By Email RSS Feeds: Highly Sensitive SensoLyte® HDACs and HATs Assay Kits for Epigenetics Research AnaSpec has developed a series of highly sensitive assay kits for the detection of the activities of HDAC (Histone Deacetylase), SIRT (Sirtuin) 1 & 2 or HAT (Histone Acetyltransferases).Covalent modification of histone proteins through acetylation and deacetylation affects chromatin structure and regulates gene expression.The Sirtuin 1 (class III) enzyme represents a target for treatment of age-related diseases and type II diabetes.These assays are fluorimetric, some of which are FRET (fluorescence resonance energy transfer)-based.Histones are the chief protein components of chromatin.Covalent modification of histone proteins through acetylation and deacetylation affects chromatin structure and regulates gene expression.