Pandion Pulls In $80M as Ulcerative Colitis Drug Advances in Clinic

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Pandion is developing drugs intended to treat autoimmune diseases by fixing the immune system imbalance that leads to these conditions. The Cambridge, MA-based biotech’s drugs are proteins and antibodies engineered to home in on a site of autoimmune disease or inflammation. Last month, the company dosed the first patient in a Phase 1 study in ulcerative colitis, a disease characterized by inflammation of the inner lining of the large intestine. In addition to its internal R&D, Pandion also has a partnership with Astellas Pharma focused on developing treatments for type 1 diabetes and other autoimmune diseases of the pancreas. Its pipeline includes compounds in preclinical development for autoimmune disorders of the liver and the skin, kidney conditions, and type 1 diabetes.

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