Swift Biosciences Launches Normalase™, Radically Streamlining and Improving NGS Library Normalization
Summary
Normalase provides an efficient, robust, scalable and cost-effective means to significantly reduce and simplify the work necessary for accurately loading balanced libraries on sequencing instruments. "Normalase is quant-free, bead-free, and allows bulk processing to save you time and obtain more evenly balanced sequencing data." Today, prior to sequencing, NGS library normalization requires numerous pipetting steps, calculation of sample-specific volumes and dilutions, purchase of quantification consumables and instrumentation, and finally analysis of quantification data to dilute and pool libraries to appropriate concentrations. Normalase condenses all of these pain points down to a simple, 2-step workflow with uniform sample processing by cutting out the need for conventional library quantification and normalization. Because of the unique workflow, Normalase also mitigates index hopping for libraries sequenced on patterned flow cells.