What are the Major Peripheral Artery Disease Risk Factors?

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Additionally, the plaque in the arteries can rupture, resulting in a clot that can limit the flow of blood further. Tobacco smoke contains chemicals that can damage blood vessels, and at the moment your body attempts to heal the harm, plaque can develop. The illness also puts you at risk of nerve damage, which makes it hard for you to feel foot or leg injuries. Cholesterol consists of substances, such as fat and calcium, which can accumulate in plaque form in your blood vessels. In some cases, it may be possible to lower the risk of contracting PAD, depending on the age, other health conditions and lifestyle.

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