Does SYLVIA propose a synthetic route how to synthesie a chemical compound in the lab? | MN-AM

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No, SYLVIA does not perform a retrosynthetic analysis of a synthesis target compound and does not propose a synthetic route how to synthesie a chemical compound in a chemistry laboratory. SYLVIA is a tool for the estimation of the synthetic accessibility of organic, typically drug-like molecules. SYLVIA ranks compounds on a scale from 1 to 10 regarding if a compound is easy to synthesize in an organic chemistry lab (low SYLVIA score) or if it is a difficult synthesis target (high SYLVIA score). SYLVIA is used to rank and prioritize compounds according to the ease of synthesis, e.g., for virtually generated or (drug-) targeted compound libraires or collections.

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