Unable to open PDF. Something went wrong. A running instance of Acrobat has caused an error. | Community

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Summary

Adobe Acrobat users are experiencing a bug in version 24.005.20421 that can prevent PDFs from opening after they are saved to a network location. The error appears when Acrobat spawns multiple background tasks and shows a message about a running instance causing an error. Adobe recommends ending Acrobat tasks, changing a registry DWORD setting, and restarting the computer as a workaround. Adobe says it will include a permanent fix in its March update.

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