C The Signs Raises $8 Million From Khosla Ventures
Summary
C the Signs, the creator of an AI-based platform to identify patients at risk of cancer at the earliest and most curable stage, announced $8 million in funding from Khosla Ventures. And the companys explainable AI model works by analyzing data already available in inpatient electronic health records, going beyond fundamental risk indicators like age and gender to examine a vast number of personal and environmental data points to assess an individuals cancer risk precisely. By personalizing risk profiles, the platform flags people who need targeted testing and rules out those who do not while reducing the burden on primary care physicians.C the Signs recently unveiled new data at the 2025 ASCO Gastrointestinal Cancers Symposium using its AI model on the records of 894,275 patients registered in the Mayo Data Platform to achieve a sensitivity of 93.8% comparable to the sensitivity level of a colonoscopy and a specificity of 19.7% in identifying patients at risk of colorectal cancer. Instead, we want to enable primary care physicians to identify cancer risk at the earliest possible stage, to substantially increase the chance of survival. As a physician and a former leader of several large health systems, this is exactly the kind of transformative tool that not only works to improve outcomes, but reduces gaps in care.