Duquesne Receives New $1.5 Million Grant to Expand Transplantation Research

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PITTSBURGH, Aug. 13, 2024 /PRNewswire/ -- Duquesne University has received a new $1.5 million grant that will expand research into using nanoparticle technology to preserve human limbs for transplantation surgeries.The grant awarded to Dr. Jelena M. Janjic of Duquesnes School of Pharmacy will create novel preservation strategies for multiple tissue types, including skin, bone, nerves and blood vessels. "The proposed technology is a breakthrough advance beyond current standard of care options," said Janjic, associate professor of pharmaceutical sciences at Duquesne and founder and co-director of the universitys Chronic Pain Research Consortium. Faron Pharmaceuticals, a Finnish drug discovery company, and BMIOrganbank, a leader in clinical and research solutions for organ preservation, are industry collaborators on the project."Dr. A key benefit of the quality by design process is that the nanoparticles can be manufactured on a large scale, as will be required for clinical use, Janjic said. "Janjic, who created the first inflammatory pain nanomedicine targeted to immune cells, added that reducing tissue damage could extend the donor allocation time and distance of transportation, allowing development of a national matching system for bone marrow and cord blood transplants.

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