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The acquisition of Cone Health is part of an ambitious effort to build a national network that combines insurance and care. Speedy weight loss from drugs used to fight obesity and diabetes has left some users looking gaunt and aged. The boss of Swiss skincare group Galderma thinks treatments for what has been dubbed "Ozempic face" could give the company a lift. The company is hoping to boost revenue by selling a new platform that uses artificial intelligence to help store and analyze contracts. Australian money manager Perpetual sold off some government bonds and cut its cash holdings in its flagship fixed-income fund following the Federal Reserves recent decision to reduce its balance sheet at a slower pace.

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