Dandelion Health Launches GLP-1 Data Library To Advance Precision Medicine
Summary
Unlocking the depth of clinical data for GLP-1 treatment discovery Life sciences and other research organizations can use the GLP-1 data library for a range of use cases, including: • Evaluating the quality of weight loss through biomarkers found in body scans; • Comparing the efficacy of treatments head-to-head across a range of different real-world measures; • Demonstrating GLP-1s therapeutic effects beyond current uses, including secondary benefits derived from exploratory use or demonstrated with additional data modalities; • Quantifying any side effects associated with GLP-1 use; and/or • Developing precision-medicine tools to identify patients with uncontrolled symptoms or to match patients to the right treatment plans. "Our goal was to curate a dataset that captures the full range of benefits that this new class of emerging treatments can offer — based on a larger and more representative patient population than would traditionally be seen in clinical trials," said Shivaani Prakash, Dandelions Head of Data. One example includes researchers from a large academic medical center who developed an algorithm that segments abdominal CTs to quantify fat loss and muscle and bone preservation. The project seeks to evaluate the impact of GLP-1s on overall body composition — far more indicative of treatment efficacy compared to weight loss, which is limited to what can be measured by structured data like BMI. Dandelion also has conducted its own research project using the librarys structured EHR data to evaluate GLP-1s efficacy across real-world patient cohorts and demographic groups; the relationship between persistence or duration of treatment and clinical outcomes; as well as observable GLP-1 effects on other comorbidities that may suggest adjacent indications.